Port Isabel is located right on the Laguna Madre Bay and the Gulf of Mexico. We are known for our excellent seafood and quality local restaurants and dining. Come and eat in Port Isabel. Dine on the bay or have some excellent Mexican, Italian or American cuisine. There is something for everyone in Port Isabel restaurants. We also boast excellent fresh fish and shrimp for sale at our excellent seafood markets. Come and enjoy a fabulous meal in Port Isabel.